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Infection Recognition Molecules


🍀Infection Recognition Molecules

🟠In the innate immune system, this involves interaction between Pathogen Associated Molecular Patterns (PAMPs) and Pattern Recognition Receptors (PRRs).

🟠 In the adaptive immune system, this involves interaction between Major Histocompatibility Complexes (MHCs) and T cells.

🍀Pattern Recognition Receptors

🔵The innate immune system is rapid and non-specific, quickly phagocytosing foreign cells. It uses Pattern Recognition Receptors (PRRs) to recognise pathogens.

🔵Pattern Recognition Receptors are infection recognition receptors located on immune cells such as macrophages and dendritic cells. They bind to Pathogen Associated Molecular Patterns (PAMPs).

🔵A PAMP is a specific arrangement of carbohydrates, lipids and nucleic acids on the surface of a pathogen that signals to a phagocyte that a cell is foreign.

🔵Many different molecules can act as PAMPs, including peptidoglycans, endotoxin and flagellin.

#immunology

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